Home 
Reagents/Kits Blood Grouping Reagents Anti Lea (monoclonal)
Reagents/Kits Blood Grouping Reagents Anti Lea (monoclonal)
Blood Grouping Reagents
Anti Lea (monoclonal)
The Lewis system antigens are not an integral part of the red cell membrane and are produced by tissue cells and found primarily in plasma and watery secretions. Red cells acquire Lewis antigens by absorption from surrounding plasma. The amount of Lewis antigen expressed on a cell can vary with the cell’s ABO phenotype. Anti-Lea and Anti-Leb have not been associated with Haemolytic Disease of the Newborn, but examples of Anti-Lea have caused Haemolytic Transfusion Reactions.
The reagents will cause agglutination (clumping) of test red cells, that carry the corresponding Lewis antigen, after centrifugation. No agglutination generally indicates the absence of the corresponding Lewis antigen (see Limitations).
Lorne Monoclonal Anti-Lea and Anti-Leb blood grouping reagents contain mouse monoclonal IgM antibodies, diluted in a phosphate buffer containing sodium chloride, EDTA, bovine albumin and macromolecular potentiators. Anti-Lea is made with Clone LEA2 and Anti-Leb is made with Clone LEB2. Each reagent is supplied at optimal dilution for use with all the recommended techniques stated below without the need for further dilution or addition. For lot reference number and expiry date see Vial Label.
The reagents will cause agglutination (clumping) of test red cells, that carry the corresponding Lewis antigen, after centrifugation. No agglutination generally indicates the absence of the corresponding Lewis antigen (see Limitations).
Lorne Monoclonal Anti-Lea and Anti-Leb blood grouping reagents contain mouse monoclonal IgM antibodies, diluted in a phosphate buffer containing sodium chloride, EDTA, bovine albumin and macromolecular potentiators. Anti-Lea is made with Clone LEA2 and Anti-Leb is made with Clone LEB2. Each reagent is supplied at optimal dilution for use with all the recommended techniques stated below without the need for further dilution or addition. For lot reference number and expiry date see Vial Label.
Avaliable Sizes
2ml1000ml
Contact
Info Request
|
To receive more info or to request a quote please fill in the form below. Required * |
Coombs Control Cells - 970
In 1945, Coombs, Mourant and Race described the use of anti-human globulin serum for detection of red cell-bound non-agglutinating antibodies and the antiglobulin (Coombs) test was rapidly applied. One cause of false negative antiglobulin tests is improper washing of the cells which results in free globulin molecules being present with supposedly washed cells and these globulins neutralise the antiglobulin serum when it is added. A negative result in an antiglobulin test should only occur when anti-human globulin is added to red cells that are not sensitised. To show that test cells were properly washed and that no neutralisation has occurred, antibody-coated cells are used as a positive indicator.
Anti Jka - 323
The Jka and Jkb antigens were reported in 1951 and 1953 respectively. Anti-Jka and anti-Jkb can both show dosage and are notorious for their evanescence: antibody titres that rise after stimulation but quickly drop, often to undetectable levels. Kidd system antibodies have been implicated in delayed and immediate Haemolytic Transfusion Reactions and Haemolytic Disease of the Newborn.
Anti H Lectin
The H antigen is part of the Hh system and is found on all red cells except those of Oh (hh) Bombay phenotype, which is extremely rare. H is the precursor of A and B and so group A and B people have less H than O people.
Toxoplasmosis Latex Test Kit - 033
When used by the recommended techniques, latex particles in the reagent will agglutinate (clump) in the presence of Toxoplasma gondii antibodies. No agglutination generally indicates absence of the Toxoplasma antibody
Anti Lea (monoclonal)
The Lewis system antigens are not an integral part of the red cell membrane and are produced by tissue cells and found primarily in plasma and watery secretions. Red cells acquire Lewis antigens by absorption from surrounding plasma. The amount of Lewis antigen expressed on a cell can vary with the cell’s ABO phenotype. Anti-Lea and Anti-Leb have not been associated with Haemolytic Disease of the Newborn, but examples of Anti-Lea have caused Haemolytic Transfusion Reactions.
Avaliable Sizes
If you would like A different size to the ones we have listed, please contact us with your requirement.info@lornelabs.com
Share